Breast cancer|Stomach cancer

In Breast cancer Hervycta 440 + Injection is used to treat breast cancer when other medicines have failed to show significant improvement. It helps to stop cancer growth and further spread and relieves the symptoms of breast cancer such as breast lumps bloody discharge from nipple or changes in the shape or texture of the breast. This medicine is given as an injection by a doctor or nurse. Follow your doctor’s instructions carefully to get the most benefit.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Hervycta 440 + Injection is used in the treatment of breast and stomach cancer. It works by killing the cancer cells by inhibiting HER2 (human epidermal growth factor receptor protein).Hervycta 440 + Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.The most common side effects of this medicine include nausea headache rash insomnia and infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood thereby increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart liver and blood uric acid levels. You must have to inform your doctor if you experience breathlessness cough shivering swelling of legs and arm.Many other medicines can affect or be affected by this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

- Alcohol : UNSAFE <p> Hervycta 440 + Injection may cause excessive drowsiness with alcohol. | - Pregnancy : CONSULT YOUR DOCTOR <p> Hervycta 440 + Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. | - Breast feeding : CONSULT YOUR DOCTOR <p> Hervycta 440 + Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. | - Driving : CONSULT YOUR DOCTOR <p> It is not known whether Hervycta 440 + Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. | - Kidney : SAFE IF PRESCRIBED <p> Hervycta 440 + Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Hervycta 440 + Injection may not be needed in these patients. Please consult your doctor. | - Liver : CONSULT YOUR DOCTOR <p> There is limited information available on the use of Hervycta 440 + Injection in patients with liver disease. Please consult your doctor.

If you miss a dose of Hervycta 440 + Injection please consult your doctor.

Chemical Class :: Monoclonal antibody (mAb)|Habit Forming :: No|Therapeutic Class :: ANTI NEOPLASTICS|Action Class :: HER2/neu (ErbB2) Inhibitor- Monoclonal antibody

Breast cancer|Stomach cancer

Anemia (low number of red blood cells) | Chills | Common cold | Cough | Decreased blood cells (red cells white cells and platelets) | Diarrhea | Fatigue | Fever | Headache | Heart failure | Infection | Insomnia (difficulty in sleeping) | Mucosal inflammation | Nausea | Rash | Stomatitis (Inflammation of the mouth) | Taste change | Upper respiratory tract infection | Weight loss

UNSAFE

CONSULT YOUR DOCTOR

CONSULT YOUR DOCTOR

CONSULT YOUR DOCTOR

SAFE IF PRESCRIBED

CONSULT YOUR DOCTOR

Q. What are the serious side effects of Hervycta 440 + Injection?::: There are various side effects related to Hervycta 440 + Injection such as sore throat fever chills excessive tiredness pale skin nosebleeds and other unusual bruising or bleeding. One can also experience stomach pain seizures hallucinations muscle cramps and spasms. Along with that nausea or vomiting loss of appetite fatigue rapid heart beat discoloration of urine; decreased amount of urine difficulty in urinating pain when urinating and other signs of infection can also be observed with the use of Hervycta 440 + Injection. You should call your doctor immediately if you notice any such symptoms.| Q. How long after Hervycta 440 + Injection therapy can I get pregnant?::: Women of child-bearing age should use effective contraception during Hervycta 440 + Injection therapy and for 7 months after completing the treatment. You can plan your pregnancy after 7 months of treatment with Hervycta 440 + Injection.| Q. How long should Hervycta 440 + Injection be taken?::: Patients with early breast cancer should take Hervycta 440 + Injection for 1 year or until disease recurs whichever occurs first. It is not advised to extend the treatment beyond 1 year in patients of early breast cancer.| Q. Is fasting required before administering Hervycta 440 + Injection? ::: No fasting is not required before administering Hervycta 440 + Injection. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.| Q. How is Hervycta 440 + Injection given intravenously or intramuscularly?::: There are 2 different formulations available for administration of Hervycta 440 + Injection one is given as an infusion into a vein (intravenous infusion) and the other is given as an injection under the skin (subcutaneous injection). It is important to check the product labels to ensure that the correct formulation is being given as prescribed. Hervycta 440 + Injection intravenous formulation is not for subcutaneous use and should be given as an intravenous infusion only. Your doctor may consider switching your Hervycta 440 + Injection intravenous treatment to Hervycta 440 + Injection subcutaneous treatment (and vice versa) if considered appropriate for you.| Q. Can Hervycta 440 + Injection be given to HER2 negative cancer patients?::: No Hervycta 440 + Injection cannot be given in patients with HER2 negative cancer cells. Hervycta 440 + Injection belongs to class of monoclonal antibody. It binds selectively to a protein called human epidermal growth factor receptor 2 (HER2). HER2 is found in large amounts on the surface of some cancer cells. When Hervycta 440 + Injection binds to HER2 it stops the growth and spread of the cancer cells. Therefore it is only effective in HER2 positive patients (in which HER2 is present) and will not be beneficial for HER2 negative patients (in which HER2 is not present).| Q. Why has my doctor advised for investigations of heart?::: Hervycta 440 + Injection when used with anthracycline class of anti-cancer medicines (eg doxorubicin) may adversely affect your heart. Hence your doctor needs to check the health of your heart initially before starting treatment and during treatment.| Q. How frequently heart investigations are required?::: Heart investigations should be performed at the starting of the treatment. It should be repeated every 3 months during treatment and every 6 months after the discontinuation of treatment until 24 months from the last administration of Hervycta 440 + Injection. Those patients who already have heart-related problems will require investigations every 12 weeks.