Breast cancer

In Breast cancer Combinib 250mg Tablet helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps bloody discharge from nipples or changes in the shape or texture of the breast. Combinib 250mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew crush or break it. Combinib 250mg Tablet is to be taken empty stomach.

Combinib 250mg Tablet is used in the treatment of breast cancer. It works by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced-stage breast cancer.Combinib 250mg Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.The most common side effects of this medicine include nausea headache back pain and breathing difficulty. It may cause severe diarrhea drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine. Inform your doctor if you notice a severe headache confusion problems with your eyesight nausea or vomiting. Your doctor may check your liver function before during and after treatment with this medicine.Before taking Combinib 250mg Tablet let your doctor know if you have liver or kidney problems. Many other medicines can affect or be affected by this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.There is a Patient Support Program/Patient Assistance Program available in India for this medicine being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew crush or break it. Combinib 250mg Tablet is to be taken empty stomach.

- Alcohol : CONSULT YOUR DOCTOR <p> It is not known whether it is safe to consume alcohol with Combinib 250mg Tablet. Please consult your doctor. | - Pregnancy : CONSULT YOUR DOCTOR <p> Combinib 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. | - Breast feeding : UNSAFE <p> Combinib 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. | - Driving : UNSAFE <p> Combinib 250mg Tablet may cause side effects which could affect your ability to drive. | - Kidney : CAUTION <p> Combinib 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor.Limited information is available on the use of Combinib 250mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. | - Liver : CAUTION <p> Combinib 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor.Limited information is available on the use of this medicine in patients with the severe liver disease.

If you miss a dose of Combinib 250mg Tablet consult your doctor.

Chemical Class :: Quinazolinamines Derivative|Habit Forming :: No|Therapeutic Class :: ANTI NEOPLASTICS|Action Class :: Tyrosine kinase inhibitors

Breast cancer

Abdominal pain | Back pain | Breathing problems | Constipation | Cough | Diarrhea | Fatigue | Headache | Hot flashes | Increased bilirubin in the blood | Insomnia (difficulty in sleeping) | Joint pain | Liver damage | Loss of appetite | Mucosal inflammation | Nausea | Pain in extremities | Rash | Stomatitis (Inflammation of the mouth) | Vomiting | Weakness | Weight gain

Q. Is Combinib 250mg Tablet a chemotherapy medicine?::: No this is a targeted drug that belongs to a class of anti-cancer medicines. They are more specific than chemotherapy in their mechanisms of action. Combinib 250mg Tablet belongs to the tyrosine kinase inhibitors group of medicines. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop or slow the spread of cancer cells.| Q. Can Combinib 250mg Tablet be given in combination with other anti-cancer drug?::: Yes Combinib 250mg Tablet can be used with other anti-cancer drugs. Generally it is used in combination with capecitabine to treat advanced breast cancer in patients who have already been treated with chemotherapy. Combinib 250mg Tablet is also used with letrozole to treat breast cancer in post-menopausal women.| Q. How should I take Combinib 250mg Tablet?::: You should take Combinib 250mg Tablet exactly as advised by your doctor. Swallow Combinib 250mg Tablet tablets whole with a glass of water at the same time each day. You must take Combinib 250mg Tablet 1 hour before or 1 hour after meals and at the same time concerning food each day (e.g. you could always take your tablet one hour before breakfast).| Q. Does Combinib 250mg Tablet have any effect on liver?::: Combinib 250mg Tablet may cause liver damage which can be severe or life-threatening. Liver damage can occur as soon as several days or as late as several months after the start of treatment with Combinib 250mg Tablet. Inform your doctor if you have or had liver disease. If you experience any of the symptoms such as itching change in color of the skin or eyes (yellowing) discoloration of urine pain in the upper right part of the stomach unusual bleeding or bruising or pale or dark stools call your doctor immediately.| Q. How should I manage diarrhea while taking Combinib 250mg Tablet?::: If you suffer from diarrhea while taking Combinib 250mg Tablet you should drink plenty of fluids (8 to 10 glasses a day) such as water sports drinks or other clear liquids. You should eat low-fat high protein foods instead of fatty or spicy foods. Eating cooked vegetables instead of raw vegetables and removing the skin from fruits before eating can also be helpful. Try to avoid milk and milk products (including ice cream) and herbal supplements (some may cause diarrhoea). Inform the doctor if the condition persists who may interrupt the treatment depending on the severity of diarrhea.| Q. How can I take care of my skin while on Combinib 250mg Tablet?::: Your doctor will check your skin before and during the treatment. If you have sensitive skin use a soap-free cleanser and beauty products that are fragrance-free and hypoallergenic. It is also advised that you use sunscreen with an SPF (Sun Protection Factor) of 30 or higher. Inform your doctor immediately if you get a rash.| Q. What tests will the doctor advise before starting Combinib 250mg Tablet?::: You may need extra tests to check that your heart and liver are working properly. Combinib 250mg Tablet may change the way your heart beats and pumps blood through your body. Your doctor will monitor you carefully to see whether Combinib 250mg Tablet has affected your heart. Along with that your doctor will get your liver function investigated. Based on the results of these tests the doctor will decide whether dose adjustment or discontinuation of treatment is required.| Q. How long after Combinib 250mg Tablet can I plan pregnancy?::: Use an effective method of contraception to avoid pregnancy while you are taking Combinib 250mg Tablet and continue for at least 1 week after the last dose. Inform your doctor if you become pregnant who will decide whether to stop or continue treatment.