Darmaseal Cream contains Zinc Oxide - 40% w/w. Role of key ingredients:Zinc oxide is a topical skin product which is used as a protective coating for mild skin irritations and abrasions.Zinc Oxide is used to prevent and treat diaper rash minor skin irritations by forming a protective barrier between the skin and the diaper. Darmaseal cream protects the skin from rashes and other skin irritations and also used to treat a variety of inflammatory allergic or itchy skin disorders. Direction to use: Apply Darmaseal Cream Topically with each diaper change. Use under medical supervision.